This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (6)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in JAMA  Social Bookmarking   What's this?

Matthew Hotopf, MBBS, MSc, PhD, MRCPsych

JAMA. 2003;289:1436-1437.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The Veterans Affairs (VA) Cooperative Study #470, a trial of cognitive behavioral therapy (CBT) and aerobic exercise for Gulf War veterans' illnesses (GWVI) reported in this issue of THE JOURNAL,¹ is a remarkable achievement. It is the first credible trial of an intervention for symptomatic Gulf War veterans, and with 1092 individuals randomized at 20 sites, it is one of the largest trials of a psychotherapeutic intervention ever published. The study used a factorial design to randomize symptomatic veterans who received usual care, CBT, graded exercise therapy, or both in combination. The results suggest that CBT leads to a modest reduction in physical disability (the primary outcome measure), graded exercise has no such effect, and the combined treatments can lead to improvements in fatigue and cognitive symptoms but not pain. The modest effects shown in the primary outcome are difficult to interpret. Should all . . . [Full Text of this Article]

Author Affiliation: Gulf War Illness Research Unit, Guy's King's and St Thomas' School of Medicine, King's College, London, England.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Cognitive Behavioral Therapy and Aerobic Exercise for Gulf War Veterans' Illnesses: A Randomized Controlled Trial
Sam T. Donta, Daniel J. Clauw, Charles C. Engel, Jr, Peter Guarino, Peter Peduzzi, David A. Williams, James S. Skinner, André Barkhuizen, Thomas Taylor, Lewis E. Kazis, Stephanie Sogg, Stephen C. Hunt, Cynthia M. Dougherty, Ralph D. Richardson, Charles Kunkel, William Rodriguez, Edwin Alicea, Philippe Chiliade, Margaret Ryan, Gregory C. Gray, Larry Lutwick, Dorothy Norwood, Samantha Smith, Michael Everson, Warren Blackburn, Wade Martin, J. McLeod Griffiss, Robert Cooper, Ed Renner, James Schmitt, Cynthia McMurtry, Manisha Thakore, Deanna Mori, Robert Kerns, Maryann Park, Sally Pullman-Mooar, Jack Bernstein, Paul Hershberger, Don C. Salisbury, and John R. Feussner
JAMA. 2003;289(11):1396-1404.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

There is only one functional somatic syndrome
Wessely and White
Br. J. Psychiatry 2004;185:95-96.
FULL TEXT  

The Long Aftermath of the 1991 Gulf War
Wessely
ANN INTERN MED 2004;141:155-156.
FULL TEXT