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Cutaneous Vascular Malformations in Disappearing Bone (Gorham-Stout) Disease
Daniela Bruch-Gerharz, MD;
Claus-Dieter Gerharz, MD;
Helger Stege, MD;
Jean Krutmann, MD;
Michael Pohl, MD;
Rainer Koester, MD;
Thomas Ruzicka, MD
JAMA. 2003;289:1479-1480.
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A 34-year-old man was referred to our hospital for evaluation of extensive and slowly progressive vascular skin lesions and recurrent episodes of local cutaneous infection. He had a history of cutaneous lymphatic malformations of the left lower extremity since he was 14 years old. After sustaining minor trauma at age 21 years, the patient was hospitalized for diffuse left leg pain without associated constitutional symptoms. The patient had no personal or family history of systemic vascular malformations. A definite diagnosis was not made.
During the following year, the patient developed difficulty walking and severe progressive bone pain in his left leg, which was exacerbated by physical activity. He was referred to a radiology center with special expertise in the diagnosis of bone disease for further evaluation. Radiographs taken at . . . [Full Text of this Article]
Author Affiliations: Departments of Dermatology (Drs Bruch-Gerharz, Stege, Krutmann, and Ruzicka), Pathology (Dr Gerharz), and Radiology (Dr Pohl), Heinrich-Heine-University of Düsseldorf, Düsseldorf, Germany; and the Institute of Radiology (Dr Koester), Lukas-Krankenhaus, Neuss, Germany.
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