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The Need for Regulation of Dietary Supplements—Lessons From Ephedra
Phil B. Fontanarosa, MD;
Drummond Rennie, MD;
Catherine D. DeAngelis, MD, MPH
JAMA. 2003;289:1568-1570.
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Dietary supplements encompass a wide spectrum of products, including vitamins and minerals, such as folate and calcium; herbal therapies and botanical agents, such as ephedra and ginkgo biloba; and enzymes or extracts from organs or glands, such as some "hormone" preparations.1 Dietary supplements are readily available in pharmacies, grocery stores, and health food stores, as well as by mail and via the Internet. These products are widely promoted, often with unsubstantiated claims of benefit and rarely with any mention of potential hazards. In the United States, dietary supplements are used by millions of people every day and account for billions of dollars in sales annually.
Dietary supplements are regulated by the US Food and Drug Administration (FDA), although under different regulations than those governing prescription medications and over-the-counter drugs.1 The Dietary Supplement Health and Education Act (DSHEA) of . . . [Full Text of this Article]
Author Affiliations: Dr Fontanarosa is Executive Deputy Editor, Dr Rennie is Deputy Editor, and Dr DeAngelis is Editor, JAMA.
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