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To the Editor: Between 1978 and 1979, more than 2000 people in Taiwan ingested rice oil contaminated with polychlorinated biphenyls (PCBs) and their pyrolytic product, mainly polychlorinated dibenzofurans (PCDFs). This event has been referred to as the "Yucheng exposure."¹ A previous study of the sperm of young men born to Yucheng women exposed to PCBs/PCDFs showed increased abnormal morphology, reduced motility, and reduced capacity to penetrate hamster oocytes.² Effects of postnatal exposure to PCBs/PCDFs on sperm quality, however, are less well documented. We assessed the sperm quality of men directly exposed to PCBs/PCDFs in the Yucheng exposure.

Methods

In 1991, a matched control group was identified for members of a registry of individuals exposed to the Yucheng event.³ We used the 1979 addresses of the registry members as index addresses and attempted to identify persons who lived nearby in 1979 from the archives of the registration offices. We began with a . . . [Full Text of this Article]

Corresponding Author: Yueliang Leon Guo, MD, MPH, PhD, Department of Occupational & Environmental Health, National Cheng Kung University Medical College, 138 Sheng Li Rd, Tainan 70428, Taiwan (e-mail: leonguo@mail.ncku.edu.tw).

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