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TIME for Reflection

Eric D. Peterson, MD, MPH

JAMA. 2003;289:1157-1158.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The pace of scientific discovery and medical care delivery accelerates with each passing year. Physicians faced with an overwhelming number of publications strive to rapidly extract a study's "bottom line" (ie, how can these findings be distilled into simple heuristics, or rules of thumb, for patient care). While such a reductionist approach is understandable, some areas of medicine defy such simplification. The 1-year results of the Trial of Invasive versus Medical therapy in Elderly patients (TIME) study, published in this issue of THE JOURNAL,¹ clearly exemplify this situation.

The TIME study addresses the benefit of routine invasive management (cardiac catheterization and revascularization) in elderly patients with symptomatic coronary artery disease. Many physicians are facing this vexing clinical issue with increasing frequency. Patients aged 75 years or older represent a third of those hospitalized with acute ischemic events and account for more than half of all . . . [Full Text of this Article]

Author Affiliation: Department of Cardiology, Duke University Medical Center, Durham, NC.

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Outcome of Elderly Patients With Chronic Symptomatic Coronary Artery Disease With an Invasive vs Optimized Medical Treatment Strategy: One-Year Results of the Randomized TIME Trial
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