This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (15)  • Contact me when this article is cited  Related Content  • Related letters  • Related article  • Similar articles in JAMA  Topic Collections  • Occupational and Environmental Medicine  • Pulmonary Diseases  • Asthma  • Immunology  • Allergy  • Alert me on articles by topic  Social Bookmarking   What's this?

George D. Thurston, ScD; David V. Bates, MD

JAMA. 2003;290:1915-1917.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

For nearly 100 years it has been known that asthma is a condition in which an acute respiratory response may follow inhalation of some material to which a person is sensitized. The list of such materials grew slowly over 50 years (it started with horse dandruff), continued with ragweed and grasses, and on the basis of skin responses, was believed to include a wide variety of foodstuffs (including nuts).¹ Domestic pets, and later, pests such as cockroaches and house dust mites came to the fore, and as occupational asthma came to be recognized, the list expanded still further. However, the focus of such awareness has been on agents that directly cause allergic reaction, and therefore can be diagnosed via skin tests, rather than on agents that cause nonspecific generalized inflammation, such as air pollution.

Recognition that exacerbations of asthma commonly involve inflammation . . . [Full Text of this Article]

Author Affiliations: Nelson Institute of Environmental Medicine, New York University School of Medicine, Tuxedo (Dr Thurston) and Department of Medicine, University of British Columbia, Vancouver (Dr Bates).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED LETTERS

Ozone and Asthma
Albert Donnay
JAMA. 2004;291(4):423.
EXTRACT | FULL TEXT  

Ozone and Asthma—Reply
George D. Thurston and David V. Bates
JAMA. 2004;291(4):423-424.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Association of Low-Level Ozone and Fine Particles With Respiratory Symptoms in Children With Asthma
Janneane F. Gent, Elizabeth W. Triche, Theodore R. Holford, Kathleen Belanger, Michael B. Bracken, William S. Beckett, and Brian P. Leaderer
JAMA. 2003;290(14):1859-1867.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Ambient air pollution triggers wheezing symptoms in infants
Andersen et al.
Thorax 2008;63:710-716.
ABSTRACT | FULL TEXT  

Gene-Air Pollution Interactions in Asthma
London
Proc Am Thorac Soc 2007;4:217-220.
ABSTRACT | FULL TEXT  

Adenosine Sensory Transduction Pathways Contribute to Activation of the Sensory Irritation Response to Inspired Irritant Vapors
Vaughan et al.
Toxicol Sci 2006;93:411-421.
ABSTRACT | FULL TEXT  

Ozone and Asthma
Donnay
JAMA 2004;291:423-423.
FULL TEXT  

Asthma Symptoms Associated with Low Levels of Air Pollution
JWatch General 2003;2003:2-2.
FULL TEXT