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Risk of Neonatal Death on Weekends vs Weekdays
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To the Editor: Dr Gould and colleagues1 found evidence of increased mortality among neonates on the weekends vs weekdays, but this difference was no longer significant after adjusting for birth weight. Such an analysis may appear to account for the higher case-mix of preterm infants that may be born on the weekends, and thus be at higher risk for neonatal mortality.
It is possible, however, that the unadjusted observation of an increased risk was an artifactual result of using births on a particular day of the week as the denominator for deaths occurring on that particular day of the week. The day of the occurrence of the death is likely to be a random event and not necessarily related to the day of birth. Differences in the mortality rate on weekends vs weekdays are a function of changes in the number of births, the number of deaths, or both. If . . . [Full Text of this Article]
Michael H. Malloy, MD, MS;
Daniel H. Freeman, PhD
University of Texas Medical Branch
Galveston
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