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Hope for Perinatal Prevention of Cerebral Palsy
Jon E. Tyson, MD, MPH;
Larry C. Gilstrap, MD
JAMA. 2003;290:2730-2732.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Advances in maternal-fetal medicine and neonatology have resulted in dramatic reductions in the mortality of high-risk infants. Unfortunately, there has been no progress in reducing the prevalence of cerebral palsy (CP),1 a group of nonprogressive motor impairment syndromes caused by lesions of the brain arising in early development. In the United States, more than 100 000 people younger than 18 years are disabled by CP.2 The human and financial costs remain extremely high.3
A fundamental problem in efforts to prevent CP is a limited understanding of its causation.2, 4-5 Two studies reported in this issue of THE JOURNAL help clarify the relationship of CP to perinatal care and complications among preterm and term infants.
The study by Crowther et al6 is a multicenter randomized trial assessing whether administration of magnesium sulfate to women at risk of preterm birth would reduce CP among very . . . [Full Text of this Article]
Author Affiliations: Department of Pediatrics (Dr Tyson) and Department of Obstetrics, Gynecology, and Reproductive Sciences (Dr Gilstrap), University of Texas Medical School, Houston.
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