This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (1)  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in JAMA  Topic Collections  • Hypertension  • Alert me on articles by topic  Social Bookmarking   What's this?

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In Reply: We thank Dr Rosenthal for bringing to our attention his finding that acarbose had a significant blood pressure–lowering effect in patients with hypertension and type 2 diabetes.¹ We did not claim that we were the first to demonstrate that acarbose could reduce hypertension. We claim that our trial is the first prospective study to find that acarbose can decrease the risk of new cases of cardiovascular disease and new cases of hypertension in patients with IGT.² As far as we know, that is still true. We also found that acarbose could reduce both systolic and diastolic blood pressure in this group of patients, an observation consistent with Rosenthal's observation in patients with hypertension and diabetes.

In response to Mr Kaiser and Dr Sawicki, our analysis was based on the results of the modified ITT sample (n = 1368).² In that sample, 49 patients in the placebo group and . . . [Full Text of this Article]

Jean-Louis Chiasson, MD; Robert G. Josse, MBBS; Ramon Gomis, MD; Markolf Hanefeld, DSC; Avraham Karasik, MD; Markku Laakso, MD for The STOP-NIDDM Trial Research Group

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLES

Acarbose for Patients With Hypertension and Impaired Glucose Tolerance
Julian H. Rosenthal
JAMA. 2003;290(23):3066.
EXTRACT | FULL TEXT  

Acarbose for Patients With Hypertension and Impaired Glucose Tolerance
Thomas Kaiser and Peter T. Sawicki
JAMA. 2003;290(23):3066.
EXTRACT | FULL TEXT  

Acarbose for Patients With Hypertension and Impaired Glucose Tolerance
Claude M. Bridges
JAMA. 2003;290(23):3066-3067.
EXTRACT | FULL TEXT  

Acarbose for Patients With Hypertension and Impaired Glucose Tolerance
José-Miguel González-Clemente, Emilio Ortega-Martínez de Victoria, Olga Giménez-Palop, and Dídac Mauricio
JAMA. 2003;290(23):3067.
EXTRACT | FULL TEXT  

Acarbose Treatment and the Risk of Cardiovascular Disease and Hypertension in Patients With Impaired Glucose Tolerance: The STOP-NIDDM Trial
Jean-Louis Chiasson, Robert G. Josse, Ramon Gomis, Markolf Hanefeld, Avraham Karasik, and Markku Laakso
JAMA. 2003;290(4):486-494.
ABSTRACT | FULL TEXT