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James W. Anderson, MD

JAMA. 2003;290:531-533.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Managing diet is the key to treating all common lipid disorders. Previous observations suggest that intensive dietary intervention can decrease serum cholesterol and low-density lipoprotein cholesterol (LDL-C) levels by approximately 30%.¹ The findings of Jenkins and colleagues² reported in this issue of THE JOURNAL indicate that intensive dietary therapy may be just as effective in reducing cholesterol levels as the starting dosage of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (statin) drug.

In their preliminary investigation, Jenkins et al randomly assigned 55 healthy hyperlipidemic men and women to receive 1 of 3 treatments: a very low-saturated-fat diet based on whole-grain wheat cereals and low-fat dairy foods (control group); the same diet plus lovastatin, 20 mg/d (statin group); or a diet high in plant sterols, soy protein, viscous fibers, and almonds (dietary portfolio group). Based on data from the 46 patients who completed the 4-week study, the authors . . . [Full Text of this Article]

Author Affiliation: Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington.

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