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To the Editor: Bronchiolitis obliterans develops when an injury of small conducting airways leads to the proliferation of granulation tissue and obliteration of the airway lumen. The histological pattern is nonspecific and can result from multiple etiologies. The clinical presentation is divided into 5 categories: toxic fume inhalation, postinfectious, connective tissue disease–associated, localized, and idiopathic.¹ Several substances have been reported to cause bronchiolitis obliterans through inhalation of toxic fumes. The distribution of these agents in the lung is determined by the size of the molecule, the duration of exposure, and the solubility of the agent.²

The inhalation of mustard gas has been reported to cause chronic bronchitis, airway hyperactivity, bronchiectasis, and pulmonary fibrosis,^3-6 but there are no reports of the occurrence of bronchiolitis obliterans. We report a patient with confirmed bronchiolitis obliterans several years after likely exposure to mustard gas in Iraq.

Report of a Case

In August 2001, we evaluated a 37-year-old male . . . [Full Text of this Article]

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