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Issues in Statin-Associated Myopathy
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To the Editor: The article by Thompson et al1 provides information highlighting a common clinical problem. The article's discussion on management did not explore any alternatives to creatine kinase (CK) measurement. Are the authors aware of any data or, in their clinical experience, have they found any other noninvasive testing, such as measurement of serum aldolase level, that assists in managing cases of statin-associated myopathy?
Dr Hyman published a similar letter in Ann Intern Med. 2002;138:1007.ED.
Mark H. Hyman, MD
Department of Medicine University of California, Los Angeles
1. Thompson PD, Clarkson P, Karas RH. Statin-associated myopathy. JAMA. 2003;289:1681-1690.
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Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.
JAMA. 2003;290:888.
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