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In Reply: In response to Dr Kim and colleagues, because of the 3 species and multiple preparations of echinacea that are commonly used, it is difficult to select a single, optimal product for study. This selection is further complicated by the lack of identification of a single constituent, or group of constituents, that is responsible for the putative clinical effects of echinacea. Thus, rather than choosing a formulation on the basis of a group of chemical constituents, we used an extract of the above-ground E purpurea plant that has been reported to be effective in treating URIs in adults.^1-2 Our study medication was standardized by comparison to the fresh-squeezed juice of the plant.

Kim et al also question the dose of E purpurea that we used. Our study medication used a highly concentrated extract (31.5-53.6:1) of the plant. Approximately 2.34 g of this extract were added to 100 mL of . . . [Full Text of this Article]

James A. Taylor, MD
uncjat@u.washington.edu
Child Health Institute
University of Washington
Seattle

Wendy Weber, ND, MPH; Leanna Standish, ND, PhD; Mary McGann, MPH, MSW
Department of Naturopathic Medicine
Bastyr University
Kenmore, Wash

Carlo Calabrese, ND, MPH
Helfgott Research Institute
National College of Naturopathic Medicine
Portland, Ore

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