This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in JAMA  Topic Collections  • Surgery  • Surgical Physiology  • Surgical Infections  • Alert me on articles by topic  Social Bookmarking   What's this?

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In Reply: Dr Hopf and colleagues note that our protocol permitted management variability. Our "real world" design allowed us to evaluate the effect of oxygen as it would be used in practice—if the benefit of hyperoxia depends upon an unrealistically tight set of cofactors, then its usefulness as a routine intervention is questionable. We acknowledged the potential biases involved. However, given that the issue faced by anesthesiologists and surgeons was whether hyperoxia should become standard practice, the practical question of our study is whether any inequalities between the groups were so large as to have concealed a significantly beneficial effect of hyperoxia. We strongly doubt this to be true. In comparing our results with those of Greif et al,¹ it is imperative to note critical differences in the patients studied. For example, 30% of their patients were transfused with an average of 3 units of blood, compared with 3% receiving . . . [Full Text of this Article]

Kane O. Pryor, MD
kopryor@yahoo.com
Department of Anesthesiology

Thomas J. Fahey III, MD
Department of Surgery

Cynthia A. Lien, MD; Peter A. Goldstein, MD
Department of Anesthesiology
Weill Medical College of Cornell University
New York, NY

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLES

Supplemental Oxygen and Risk of Surgical Site Infection
Harriet W. Hopf, Thomas K. Hunt, and Noah Rosen
JAMA. 2004;291(16):1956.
EXTRACT | FULL TEXT  

Supplemental Oxygen and Risk of Surgical Site Infection
Ozan Akça and Daniel I. Sessler
JAMA. 2004;291(16):1956-1957.
EXTRACT | FULL TEXT  

Supplemental Oxygen and Risk of Surgical Site Infection
Robert Greif and Daniel I. Sessler
JAMA. 2004;291(16):1957.
EXTRACT | FULL TEXT  

Supplemental Oxygen and Risk of Surgical Site Infection
Johann Harten, Keith Anderson, and John Kinsella
JAMA. 2004;291(16):1957.
EXTRACT | FULL TEXT  

Supplemental Oxygen and Risk of Surgical Site Infection
James T. Lee
JAMA. 2004;291(16):1957-1958.
EXTRACT | FULL TEXT  

Supplemental Oxygen and Risk of Surgical Site Infection
Martin J. O'Neill, Jr
JAMA. 2004;291(16):1958.
EXTRACT | FULL TEXT  

Surgical Site Infection and the Routine Use of Perioperative Hyperoxia in a General Surgical Population: A Randomized Controlled Trial
Kane O. Pryor, Thomas J. Fahey, III, Cynthia A. Lien, and Peter A. Goldstein
JAMA. 2004;291(1):79-87.
ABSTRACT | FULL TEXT