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Guidelines for Home- and Office-Based Blood Pressure Monitoring—Reply
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In Reply: We concur with Drs Kario and Pickering. Had the upper threshold of our target range of self-measured diastolic BP been less than 85 mm Hg, we might have achieved similar levels of blood pressure control in patients randomized to treatment based on self-measured BP compared with those treated based on office BP. However, this statement must be taken in the context of 3 important considerations.
First, we intentionally kept our target range of diastolic BP identical in randomized groups to allow blinded treatment decisions and direct comparison of our current results with those from our previous work.1 Second, use of lower BP targets for treatment based on self-measured BP or daytime ambulatory BP would have substantially altered the prevalence of white-coat hypertension. For instance, at baseline in our current trial (n = 400), the numbers of patients with white-coat hypertension were 107 (26.7%), 58 (14.5%), and 20 (5.0%) . . . [Full Text of this Article]
Jan A. Staessen, MD, PhD
jan.staessen@med.kuleuven.ac.be
Elly Den Hond, PhD
Department of Molecular and Cardiovascular Research
University of Leuven
Leuven, Belgium
Eoin T. O'Brien, MD, FRCP
Department of Clinical Pharmacology
Royal College of Surgeons in Ireland
Dublin
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