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In Reply: In response to Dr Rimland, the Statens Serum Institut is the national center for prevention and control of infectious diseases in Denmark. It is a nonprofit state enterprise under the auspices of the Danish Ministry of Health and Interiors. Thus, any profit belongs to the state.

This governmental research institute in many ways resembles the Centers for Disease Control and Prevention in the United States. With regard to vaccines, the institute has a law-regulated obligation to ensure the national supply of vaccines used in the Danish childhood vaccination program. To fulfill this obligation, the institute produces some vaccines and buys other vaccines from third parties. For many years (since 1992), it has been the institute's strategy to develop and use vaccines without preservatives.

In response to Ms Bernard, we do not agree that autism cases are lost retrospectively from the Danish Psychiatric Central Register.¹ This registry is a . . . [Full Text of this Article]

Anders Hviid, MSc; Mads Melbye, MD, PhD
Department of Epidemiology Research
Statens Serum Institut
Copenhagen, Denmark

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