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Evidence-Based Global Health
Pierre Buekens, MD, PhD;
Gerald Keusch, MD;
Jose Belizan, MD;
Zulfiqar Ahmed Bhutta, MD, PhD
JAMA. 2004;291:2639-2641.
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The effectiveness of many interventions to improve health in poor populations in the developing world remains untested and therefore unproven. It is sometimes assumed that what works is known and that the only challenge is to make interventions widely available to underserved populations worldwide, the so-called know-do gap. However, other than vaccination, few global health interventions are evidence-based.
Evidence-based global health requires use of the evidence from randomized controlled trials and other scientifically valid studies to evaluate global health interventions and to measure progress in improving global health. Randomized controlled trials of global public health interventions are often cluster trials, randomizing groups or communities.1-2 When evidence from randomized trials is not available or is difficult to generalize, observational studies provide useful information but must be carefully interpreted.2 Global health needs assessment and monitoring also rely . . . [Full Text of this Article]
Author Affiliations: School of Public Health and Tropical Medicine, Tulane University, New Orleans, La (Dr Buekens); School of Public Health, Boston University, Boston, Mass (Dr Keusch); Latin American Center for Perinatology (Pan American Health Organization, World Health Organization), Montevideo, Uruguay (Dr Belizan); Husein Lalji Dewraj Professor of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan (Dr Bhutta).
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