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C-Reactive Protein and Risk of Colon Cancer
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To the Editor: Dr Erlinger and colleagues1 reported that plasma CRP levels are higher among individuals who subsequently develop colon cancer. The authors also found that even though smokers had higher CRP levels, this interaction was not associated with an increase in the risk for subsequent development of colon cancer. These findings suggest that the cause of the elevation of CRP was important in determining whether high CRP levels increased the chance for subsequent development of colon cancer.
Abu-Abid et al2 reported a link between obesity and the risk of development of colon cancer. The link between obesity and increased levels of CRP is also well documented.3 Thus, the link between elevated incidence of colon cancer and increased levels of CRP might be a reflection of the link between obesity-related increased CRP and colon cancer.
Erlinger et al considered body mass index (BMI, calculated as weight in kilograms divided by . . . [Full Text of this Article]
Moutasim H. Al-Shaer, MD
moutasim-al-shaer@uiowa.edu
Department of Internal Medicine
University of Iowa
Iowa City
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