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CLINICIAN'S CORNER
Severe Acute Pancreatitis
Vege Santhi Swaroop, MD;
Suresh T. Chari, MD;
Jonathan E. Clain, MD
JAMA. 2004;291:2865-2868.
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INTRODUCTION
In the United States, of the approximately 210 000 patients admitted to hospitals each year with acute pancreatitis,1 about 20% have severe acute pancreatitis (SAP), and primary care physicians and internists are often the first clinicians to care for these patients. In contrast to mild acute pancreatitis, which has a mortality rate of less than 1%,2 the death rate for SAP is much higher: 10% with sterile and 25% with infected pancreatic necrosis.3 Hospitalization for patients with SAP may extend beyond 2 weeks and frequently involves an intensive care unit (ICU) stay.
This review article addresses recent trends in the diagnosis and management of SAP. We searched MEDLINE from 1990 to the present using the Medical Subject Headings terms pancreatitis, acute necrotizing pancreatitis, and alcoholic pancreatitis, and the key word pancreatitis. Important clinical . . . [Full Text of this Article]
Classification and Definitions
Epidemiology and Etiology
Diagnosis
Treatment
Morbidity and Mortality
Conclusion
Author Affiliations: Division of General Internal Medicine (Dr Vege) and Division of Gastroenterology (Drs Chari and Clain), Department of Internal Medicine, Mayo Clinic, Rochester, Minn.
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