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Management of Chronic Obstructive Pulmonary Disease
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To the Editor: In their review article on the management of chronic obstructive pulmonary disease (COPD), Dr Sin and colleagues1 recommended that all patients be given pneumococcal vaccine. However, the 3 references they cite in support of this assertion2-4 discussed only the use of influenza vaccine, and none supported the use of pneumococcal vaccine. A recent Cochrane review concluded that "polysaccharide pneumococcal vaccines do not appear to reduce the incidence of pneumonia or death in adults with or without chronic illness, or in the elderly."5
Robert M. Ewart, MD
rewart@siumed.edu Department of Family & Community Medicine Southern Illinois University School of Medicine Springfield
1. Sin DD, McAlister FA, Man SFP, Anthonisen NR. Contemporary management of chronic obstructive pulmonary disease: scientific review. JAMA. 2003;290:2301-2312.
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2. Govaert TM, Thijs CT, Masurel N, Sprenger MJ, Dinant GJ, Knottnerus JA. The efficacy of influenza vaccination in elderly individuals: a randomized double-blind placebo-controlled trial. JAMA. 1994;272:1661-1665.
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3. Nichol KL, Nordin J, Mullooly J, Lask R, Fillbrandt GJ, Iwane M. Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly. N Engl J Med. 2003;348:1322-1332.
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4. Vilkman S, Keistinen T, Tuuponen T, Kivela SL. Survival and cause of death among elderly chronic obstructive disease patients after first admission to hospital. Respiration. 1997;64:281-284.
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5. Dear K, Holden J, Andrews R, Tatham D. Vaccines for preventing pneumococcal infection in adults. Cochrane Database Syst Rev. 2003;4:CD000422.
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Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.
JAMA. 2004;291:1066.
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Management of Chronic Obstructive Pulmonary DiseaseReply
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Contemporary Management of Chronic Obstructive Pulmonary Disease: Scientific Review
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