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In Reply: Dr Chu has raised a number of issues regarding our study, which he believes may have led to erroneous conclusions compared with his study.¹ First, while he describes our study as small, we had 40 participants, all of whom received laser treatment on one side of the face, and no treatment on the contralateral side. Chu's study had 41 participants, wherein only 31 participants received full-face treatments, while 10 others received sham therapy only. He raised concerns about the dropout rate in our trial, with 26 participants completing the study. In his study, 27 of 31 laser-treated participants completed the trial. As we stated in our article, we believe that our dropout rate was a reflection of patient dissatisfaction with the results.

Second, Chu pointed out that the use of an intent-to-treat basis for our data analysis may have affected the results. While this is a valid point, . . . [Full Text of this Article]

Jeffrey S. Orringer, MD
jorringe@umich.edu

Sewon Kang, MD; Timothy M. Johnson, MD; Gary J. Fisher, PhD; John J. Voorhees, MD
Department of Dermatology
University of Michigan
Ann Arbor

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