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Treatment of Acute Stroke
Still Struggling
Louis R. Caplan, MD
JAMA. 2004;292:1883-1885.
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In 1998, I wrote an editorial entitled "Stroke Treatment: Promising but Still Struggling"1 in an issue of JAMA that featured 5 articles on stroke. In that issue,2 2 articles concerned carotid artery surgery, one article reported the results of a trial of acute stroke patients receiving treatment with a heparinoid, another focused on anticoagulation in atrial fibrillation, and the fifth reviewed thrombolytic and neuroprotective treatments—each in their early years of application. During the past 6 years, there have been dramatic improvements in the technology available to diagnose stroke, and more studies have reported the results of thrombolytic therapy. This issue of JAMA includes one article on stroke diagnosis3 and 3 articles on outcomes following thrombolytic treatment with alteplase for patients with acute ischemic stroke.4-6 As these articles suggest, while there has been some progress, stroke treatment is still struggling and has a long way to go.
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Author Affiliation: Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Mass.
RELATED LETTERS
Thrombolysis for Acute Stroke
Jerry J. Svoboda
JAMA. 2005;293(4):421-422.
EXTRACT
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Thrombolysis for Acute Stroke—Reply
Louis R. Caplan
JAMA. 2005;293(4):422.
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RELATED ARTICLES
Comparison of MRI and CT for Detection of Acute Intracerebral Hemorrhage
Chelsea S. Kidwell, Julio A. Chalela, Jeffrey L. Saver, Sidney Starkman, Michael D. Hill, Andrew M. Demchuk, John A. Butman, Nicholas Patronas, Jeffry R. Alger, Lawrence L. Latour, Marie L. Luby, Alison E. Baird, Megan C. Leary, Margaret Tremwel, Bruce Ovbiagele, Andre Fredieu, Shuichi Suzuki, J. Pablo Villablanca, Stephen Davis, Billy Dunn, Jason W. Todd, Mustapha A. Ezzeddine, Joseph Haymore, John K. Lynch, Lisa Davis, and Steven Warach
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