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  Vol. 292 No. 16, October 27, 2004 TABLE OF CONTENTS
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Researchers Use Dots to Light Up Tumor Cells

Tracy Hampton, PhD

JAMA. 2004;292:1944-1945.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Much like wildlife biologists studying the comings and goings of animals in nature with devices like radiocollars, cancer investigators would relish in the opportunity to track malignant cells and watch them in action. If they could observe how tumor cells grow and spread, they might be able to come up with effective treatment strategies.

Now researchers are able to see the minute-by-minute activities of cancer cells, thanks to a new technology that uses fluorescent inorganic nanocrystals that glow under UV light. Two new studies highlight the utility of these tiny particles, called quantum dots.


Multicolor quantum dot probes injected into a mouse can detect and track multiple tumor targets (Nat Biotechnol. 2004;22:969-976). (Photo credit: Xiaohu Gao, PhD, and Shuming Nie, PhD, Emory University)

ONE CELL AT A TIME

Quantum dots could now give scientists a means to answer research questions in live organisms rather than in tissue culture and other . . . [Full Text of this Article]



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