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Tracy Hampton, PhD

JAMA. 2004;292:2072.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Some of the compounds in tobacco smoke known to cause bladder cancer in smokers are also associated with increased cancer risks in people who have never taken a puff from a cigarette. A new study has found that compounds called arylamines can be linked to bladder cancer risk in nonsmokers as well as smokers, and may account for a significant proportion of nonsmoking-related bladder cancer in the general population (J Natl Cancer Inst. 2004;96:1425-1431).

"These results give a very plausible possible explanation for a lot of the unexplained incidences of bladder cancer," said Paul Skipper, PhD, of the Massachusetts Institute of Technology, in Cambridge, and indicate that environmental sources of these carcinogens should be investigated.

UNCOVERING CAUSES

Several members of the extensive arylamine family are long known human bladder carcinogens. Approximately half of bladder cancer incidence in the United States can be attributed to cigarette smoking, and . . . [Full Text of this Article]

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