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Erectile Dysfunction in Obese Men
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To the Editor: In considering the results of the study by Dr Esposito and colleagues1 on the effect of weight reduction on erectile dysfunction in obese men, it is interesting to look at some of the older literature that addressed thiazide-induced erectile dysfunction and found improvement with weight loss among individuals who were obese.2-3 That finding becomes better explained given the improvement in endothelial function with weight loss found in the present study.
Michael Bursztyn, MD
bursz@cc.huji.ac.il Hadassah University Hospital, Mount-Scopus Jerusalem, Israel
1. Esposito K, Giugliano F, Di Palo C, et al. Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial. JAMA. 2004;291:2978-2984.
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2. Wassertheil-Smoller S, Blaufox MD, Oberman A, et al. Effect of antihypertensives on sexual function and quality of life: the TAIM Study. Ann Intern Med. 1991;114:613-620.
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3. Langford HG, Rockhold RW, Wassertheil-Smoller S, et al. Effect of weight loss on thiazide produced erectile problems in men. Trans Am Clin Climatol Assoc. 1989;101:190-194.
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Letters Section Editor: Robert M. Golub, MD, Senior Editor.
JAMA. 2004;292:2466.
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