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Biomarkers for Coronary Heart Disease: Predictive Value or Background Noise?
Mike Mitka
JAMA. 2004;292:2824-2825.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Researchers hope that the emergence of numerous biomarkers for cardiovascular disease in recent years will enable physicians to better assign risk and treat patients.
A number of patients with coronary heart disease do not exhibit traditional risk factors such as hypertension, elevated cholesterol levels, obesity, and smoking. Conversely, many individuals who do have such risk factors do not have cardiovascular disease. A nuanced understanding of biomarkers, researchers note, could increase the accuracy of risk assessment.
Biomarkersdata taken from blood or urine samplesemerged as tools for researchers to understand the pathobiology of atherothrombosis; perhaps the most common screenings are those used for cholesterol. So far, biomarkers are used mostly at the point of care for patients with acute conditions, said David Moliterno, MD, professor and chief of cardiology at the University of Kentucky in Lexington. For example, troponin measurements can show whether someone has had a high-risk myocardial infarction, . . . [Full Text of this Article] C-REACTIVE PROTEIN
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