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  Vol. 292 No. 3, July 21, 2004 TABLE OF CONTENTS
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Genes Harbor Clues to Addiction, Recovery

Tracy Hampton, PhD

JAMA. 2004;292:321-322.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Chicago—Kicking an alcohol or nicotine habit is rarely easy. But scientists analyzing the effects of various genes in addiction and recovery are finding that some individuals may have genetic variants that make it particularly difficult to overcome these dependencies.

New findings presented at the American Psychological Society's annual convention in May implicate genetic variants that affect cell surface receptors and a neurotransmitter involved in the brain's reward system. The hope is that such findings will one day enable scientists to develop new and better ways to help patients with alcohol or smoking problems.


Scientists are identifying genetic variants that may make it difficult for some individuals to overcome alcohol and nicotine dependencies. (Photo credit: Corbis)


ALCOHOL AND THE OPIOID RECEPTOR

One culprit that may play a role in how well individuals fare in alcohol rehabilitation is the µ-opioid receptor. The presence of alcohol increases brain {beta}. . . [Full Text of this Article]



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