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To the Editor: The WHI investigators¹ restricted their data on osteoporotic events to hip fractures, perhaps because of the ease of extracting the data. Had they included fractures of the spine leading to compression and kyphotic deformities, their assertion that CEE contributes no overall benefit would be difficult to justify. Getting precise data on spinal fractures presents difficulties, but as long as these common and disabling events are excluded from the data, it is erroneous to state that the burden of disease events in the CEE and placebo groups are equivalent.

Michael H. Cooper, MBCHB
cooperm@xtra.co.nz
Auckland, New Zealand

1. The Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701-1712. FREE FULL TEXT

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2004;292:685.

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