 |
|
Preimplantation Testing to Produce an HLA-Matched Donor Infant—Reply
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
In Reply: Drs Fasth and Wahlstrom point out that stem cell therapy may not be an option for ALL or AML, given the effectiveness of chemotherapy. However, given the sizeable proportion of treatment failures that Fasth and Wahlstrom note, we believe that the option of stem cell therapy should still be available for patients for whom chemotherapy is not effective, particularly if the parents plan to have another child anyway. ALL and AML are still in the list of conditions for which cord blood transplantation has been performed for many years. We agree with Dr Wagner and colleagues that preimplantation HLA typing for inherited forms of DBA should be combined with preimplantation genetic diagnosis (PGD) of DBA. However, as we mentioned in our article, all known mutations causing DBA were excluded in our cases by detailed mutation testing in parents and affected children, and this was also confirmed by the . . . [Full Text of this Article]
Anver Kuliev, MD, PhD
anverkuliev@hotmail.com
Svetlana Rechitsky, PhD;
Yury Verlinsky, PhD
Reproductive Genetics Institute
Chicago, Ill
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLES
Preimplantation Testing to Produce an HLA-Matched Donor Infant
Anders Fasth and Jan Wahlström
JAMA. 2004;292(7):803.
EXTRACT
| FULL TEXT
Preimplantation Testing to Produce an HLA-Matched Donor Infant
John E. Wagner, Jeffrey P. Kahn, Susan M. Wolf, and Jeffrey M. Lipton
JAMA. 2004;292(7):803-804.
EXTRACT
| FULL TEXT
Preimplantation Testing to Produce an HLA-Matched Donor Infant—Reply
Norman C. Fost
JAMA. 2004;292(7):804.
EXTRACT
| FULL TEXT
Preimplantation HLA Testing
Yury Verlinsky, Svetlana Rechitsky, Tatyana Sharapova, Randy Morris, Mohammed Taranissi, and Anver Kuliev
JAMA. 2004;291(17):2079-2085.
ABSTRACT
| FULL TEXT
|
