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Evidence for a 7000-Year-Old Case of Primary Hyperparathyroidism
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To the Editor: Several studies have described the importance of bone and soft tissue paleopathology in detecting and tracing various diseases from the dawn of human civilization.1-2 Skeletal manifestations of hyperparathyroidism have only rarely been identified in historic material. In the previously oldest example, from a Roman period cemetery from the Dakhleh Oasis in Egypt,3 the diagnosis was suggested by histomorphometric analysis of bone sections. We describe the findings in what we believe represents the oldest published example of hyperparathyroidism, dating to the Early Neolithic period, around 7000 years ago.
Case Description
The skeleton of a 25- to 35-year-old woman comes from an Early Neolithic cemetery from the site of Viesenhäuser Hof (Stuttgart-Mühlhausen, southwest Germany).4 The archeological record has shown that the burials belong to the Linear Band Pottery period. This was confirmed by radiocarbon dating that revealed a date for the burial site of 5100 to 4800 BCE. The skeleton . . . [Full Text of this Article]
Albert R. Zink, PhD
Division of Palaeopathology
Institute of Pathology
Academic Hospital München-Bogenhausen
Munich, Germany
Stephanie Panzer, MD
Trauma Clinic Murnau
Murnau, Germany
Martinus Fesq-Martin, PhD
Department of Physical Geography
University of Augsburg
Augsburg, Germany
Eva Burger-Heinrich, PhD
Anthro-Service
Munich
Joachim Wahl, PhD
State Office for Historical Monuments of Baden-Wurttemberg
Konstanz, Germany
Andreas G. Nerlich, MD, PhD
andreas.nerlich@extern.lrz-muenchen.de
Institute of Pathology
Academic Hospital München-Bogenhausen
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