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ABO Blood Group and Susceptibility to Severe Acute Respiratory Syndrome
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To the Editor: ABO blood group has been reported to influence susceptibility to the Norwalk virus and Helicobacter pylori infections.1-2 The prevalence of H pylori infection in Taiwan is significantly higher in patients with blood group O than in those with other blood groups,3 possibly due to a reduced number of H pylori receptors in persons with group A or group B blood. We studied the relationship between ABO blood group and the development of severe acute respiratory syndrome coronavirus (SARS-CoV) infection in a group of health care workers who were exposed to an index SARS patient and who were not wearing any personal protective equipment.
Methods
The first major SARS outbreak in Hong Kong occurred in March 2003. The index case was a patient who was admitted to Prince of Wales Hospital, a 1000-bed general hospital.4 The patient had been placed in an open ward with 20 other patients because . . . [Full Text of this Article]
Yufeng Cheng, MD, PhD;
Gregory Cheng, MD, PhD;
C. H. Chui, PhD;
F. Y. Lau, PhD
Department of Medicine & Therapeutics
Paul K. S. Chan, MBBS, MSc, MRCPath, FHKCPath
Department of Microbiology
Margaret H. L. Ng, MBChB, MRCPath
Department of Anatomical & Cellular Pathology
Joseph J. Y. Sung, MD, PhD
Department of Medicine & Therapeutics
Raymond S. M. Wong, MBChB, MRCP
raymondwong@cuhk.edu.hk
Department of Medicine & Therapeutics
Chinese University of Hong Kong
Hong Kong, China
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Inhibition of the interaction between the SARS-CoV Spike protein and its cellular receptor by anti-histo-blood group antibodies
Guillon et al.
Glycobiology 2008;18:1085-1093.
ABSTRACT
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