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Commentary by David G. Hunter, MD, PhD

JAMA. 2005;293(15):1920-1922.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

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Randomized Trial of Treatment of Amblyopia in Children Aged 7 to 17 Years

Pediatric Eye Disease Investigator Group*

Objective: To evaluate the effectiveness of treatment of amblyopia in children aged 7 to 17 years.

Methods: 49 clinical sites, 507 patients with amblyopic eye visual acuity ranging from 20/40 to 20/400 were provided with optimal optical correction and then randomized to a treatment group (2-6 hours per day of prescribed patching combined with near visual activities for all patients plus atropine sulfate for children aged 7 to 12 years) or an optical correction group (optical correction alone). Patients whose amblyopic eye acuity improved 10 or more letters (2 lines) by 24 weeks were considered responders.

Results: In the 7- to 12-year-olds (n = 404), 53% of the treatment group were responders compared with 25% of the optical correction group . . . [Full Text of this Article]

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Randomized Trial of Treatment of Amblyopia in Children Aged 7 to 17 Years
Pediatric Eye Disease Investigator Group
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