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Commentary by David G. Hunter, MD, PhD

JAMA. 2005;293(15):1920-1922.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

ARCHIVES OF OPHTHALMOLOGY

Randomized Trial of Treatment of Amblyopia in Children Aged 7 to 17 Years

Pediatric Eye Disease Investigator Group*

Objective: To evaluate the effectiveness of treatment of amblyopia in children aged 7 to 17 years.

Methods: 49 clinical sites, 507 patients with amblyopic eye visual acuity ranging from 20/40 to 20/400 were provided with optimal optical correction and then randomized to a treatment group (2-6 hours per day of prescribed patching combined with near visual activities for all patients plus atropine sulfate for children aged 7 to 12 years) or an optical correction group (optical correction alone). Patients whose amblyopic eye acuity improved 10 or more letters (2 lines) by 24 weeks were considered responders.

Results: In the 7- to 12-year-olds (n = 404), 53% of the treatment group were responders compared with 25% of the optical correction group . . . [Full Text of this Article]

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