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In Reply: Mr Paz rightly points out the relevance of cross-cultural differences in decisions about research participation, and we agree that recruitment should take these differences into account. Rather than attempting to discuss all potential determinants of participants’ decisions, the model we described flexibly incorporates many factors that are weighed. We also recommend that researchers consider a broad array of such factors when developing compensation and recruitment strategies.

Our main point is that thinking about these decisions in a basic economic framework is less limiting than other proposed ethical compensation models, which dictate few and specific determinants of payment. The "economic behavior" of our title refers to the idea that decisions reflect many monetary and nonmonetary costs and benefits. The cultural or family contexts described by Mr Paz can generate support for or against participation, which could be viewed as a cost or benefit to the individual considering participation, or . . . [Full Text of this Article]

Laura B. Dunn, MD
Ldunn@ucsd.edu
Department of Psychiatry
University of California
San Diego

Nora E. Gordon, PhD
Department of Economics
National Bureau of Economic Research
Cambridge, Mass

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