This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (70)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Topic Collections  • Psychiatry  • Alert me on articles by topic  Social Bookmarking   What's this?

David J. Kupfer, MD

JAMA. 2005;293:2528-2530.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Bipolar disorder is one of the world’s 10 most disabling conditions, taking away years of healthy functioning from individuals who have the illness.¹ With no predilection for nation, race, or socioeconomic status, classic manic-depressive illness has a prevalence of approximately 1% across all populations.² However, the personal and societal costs of bipolar disorders are not limited to the more traditional bipolar I subtype, which includes episodes of full-blown mania and major depression.³ Bipolar II disorder, involving episodes of less severe hypomania and major depression, and bipolar spectrum subtypes, which probably bring the prevalence of all bipolar disorders to more than 3% of US individuals, can also be devastating conditions. All bipolar disorders are chronically recurring illnesses associated with substantial morbidity and mortality.^4-6

The morbidity, mortality, and personal suffering associated with bipolar disorder are not simply a result of psychiatric symptoms and the attendant dysfunction. A wide . . . [Full Text of this Article]

Author Affiliation: Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pa.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Bipolar Disorder Patient Care Opportunities: Let's Answer the Call
Caley
The Annals of Pharmacotherapy 2009;43:1890-1892.
ABSTRACT | FULL TEXT  

Improving Medical and Psychiatric Outcomes Among Individuals With Bipolar Disorder: A Randomized Controlled Trial
Kilbourne et al.
Psychiatr. Serv. 2008;59:760-768.
ABSTRACT | FULL TEXT  

BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments
Maeng et al.
Proc. Natl. Acad. Sci. USA 2008;105:8766-8771.
ABSTRACT | FULL TEXT  

Antecedents and Sequelae of Sudden Parental Death in Offspring and Surviving Caregivers
Melhem et al.
Arch Pediatr Adolesc Med 2008;162:403-410.
ABSTRACT | FULL TEXT  

Cardiovascular Disease and Metabolic Risk Factors in Male Patients With Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder
Kilbourne et al.
Psychosomatics 2007;48:412-417.
ABSTRACT | FULL TEXT  

Deconstructing Bipolar Disorder: A Critical Review of its Diagnostic Validity and a Proposal for DSM-V and ICD-11
Vieta and Phillips
Schizophr Bull 2007;33:886-892.
ABSTRACT | FULL TEXT  

Identifying Functional Neuroimaging Biomarkers of Bipolar Disorder: Toward DSM-V
Phillips and Vieta
Schizophr Bull 2007;33:893-904.
ABSTRACT | FULL TEXT  

Lifetime and 12-Month Prevalence of Bipolar Spectrum Disorder in the National Comorbidity Survey Replication
Merikangas et al.
Arch Gen Psychiatry 2007;64:543-552.
ABSTRACT | FULL TEXT  

Redefining Bipolar Disorder: Toward DSM-V
Phillips and Frank
Am. J. Psychiatry 2006;163:1135-1136.
FULL TEXT