This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (8)  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in JAMA  Topic Collections  • Tuberculosis/ Other Mycobacterium  • World Health  • Pulmonary Diseases  • Pulmonary Diseases, Other  • Drug Therapy  • Drug Therapy, Other  • Infectious Diseases  • Alert me on articles by topic  Social Bookmarking   What's this?

News From the Front

Mary D. Nettleman, MD, MS

JAMA. 2005;293:2788-2790.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

During the past decade, multidrug-resistant tuberculosis (MDR-TB), defined as resistance to at least isoniazid and rifampin, has declined in the United States.¹ The number of reported MDR-TB cases has decreased from 486 in 1993 to 114 in 2003, and the proportion of resistant strains of Mycobacterium tuberculosis has decreased by half.¹ The decline is heartening but this issue of JAMA includes 2 reports from California and Russia showing why celebration would be premature.^2-3

In this issue of JAMA, Granich and colleagues² show that California has not shared in the proportionate decline of resistant strains. From 1994 to 2003, the authors analyzed the sensitivity of 28 712 culture-positive cases of TB and identified 407 MDR-TB cases. Although the absolute number of MDR-TB cases per year decreased during the 10-year period, the number of sensitive cases also declined, leading to stable proportions of resistance. Matching several databases, . . . [Full Text of this Article]

Author Affiliation: Department of Medicine, Michigan State University, East Lansing.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLES

Drug-Resistant Tuberculosis, Clinical Virulence, and the Dominance of the Beijing Strain Family in Russia
Francis Drobniewski, Yanina Balabanova, Vladyslav Nikolayevsky, Micheal Ruddy, Sergey Kuznetzov, Svetlana Zakharova, Alexander Melentyev, and Ivan Fedorin
JAMA. 2005;293(22):2726-2731.
ABSTRACT | FULL TEXT  

Multidrug Resistance Among Persons With Tuberculosis in California, 1994-2003
Reuben M. Granich, Peter Oh, Bryan Lewis, Travis C. Porco, and Jennifer Flood
JAMA. 2005;293(22):2732-2739.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Prevalence of and Molecular Basis for Tuberculosis Drug Resistance in the Republic of Georgia: Validation of a QIAplex System for Detection of Drug Resistance-Related Mutations
Gegia et al.
Antimicrob. Agents Chemother. 2008;52:725-729.
ABSTRACT | FULL TEXT  

Tuberculosis--A Global Problem Requiring a Global Solution
DeAngelis and Flanagin
JAMA 2005;293:2793-2794.
FULL TEXT