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In Reply: The study reported in Diabetes Care¹ is based on a different cohort from the JAMA study² and addressed a different question. The former examined the effect of sugars, regardless of the food source, on risk of diabetes; the latter examined the relationship between sugar-sweetened beverages, especially soft drinks, and long-term weight gain as well as risk of diabetes.

Total sugars come from a variety of foods. Some are natural sugars (from fruits and fruit juices, for example); some are added sugars from solid foods; and others are added sugars from sugar-sweetened beverages. The earlier study did not specifically examine soda consumption. Other studies have suggested that the body does not compensate for excess calories from sugar-sweetened beverages as well as it does those from solid foods, making sugary soft drinks more likely to result in a positive caloric balance and weight gain.³ In the Diabetes Care study, only . . . [Full Text of this Article]

Matthias B. Schulze, DrPH
mschulze@mail.dife.de
German Institute of Human Nutrition Potsdam-Rehbruecke
Nuthetal, Germany

JoAnn E. Manson, MD; Graham A. Colditz, MD; Meir J. Stampfer, MD; Walter C. Willett, MD; Frank B. Hu, MD
Harvard School of Public Health
Boston, Mass

David S. Ludwig, MD
Children’s Hospital
Boston, Mass

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