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  Vol. 293 No. 5, February 2, 2005 TABLE OF CONTENTS
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Comparison of MRI and CT for Detection of Acute Intracerebral Hemorrhage—Reply

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In Reply: Dr Eliasziw and Ms Paddock-Eliasziw suggest that a {kappa} statistic rather than a McNemar test for proportions could have been used to summarize the results of our study. We chose to use the McNemar test because our primary goal was to show the equivalence of MRI for detecting hemorrhage compared to CT. Had we used the {kappa} statistic, a point estimate of 0.84 would still suggest a strong correlation. Perhaps more important than the choice of statistical approach are the actual data. Acute hemorrhage was missed in 4 cases with each modality. With MRI, the hemorrhages were interpreted as chronic rather than acute in 3 patients. With CT, the hemorrhages were completely missed.

Regarding the use of a single reader rather than a panel of readers for our study, we were interested in comparing the most accurate assessment of the findings from each scan. A panel consensus reading provides . . . [Full Text of this Article]

Chelsea S. Kidwell, MD
Chelsea.Kidwell@Medstar.Net
Department of Neurology

Julio Chalela, MD
Washington Hospital Center
Washington, DC

Jeffrey L. Saver, MD
UCLA Stroke Center, UCLA Medical Center
Los Angeles, Calif

Michael D. Hill, MD; Andrew Demchuk, MD
Calgary Stroke Program, Department of Clinical Neurosciences
University of Calgary, Foothills Hospital
Calgary, Alberta

John Butman, MD; Steven Warach, MD, PhD
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, Md


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