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Alan E. Guttmacher, MD; Francis S. Collins, MD, PhD

JAMA. 2005;294:1399-1402.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In April 2003, the Human Genome Project achieved all of its original goals, including production of a finished sequence of the human genome.¹ With that historic achievement, the Human Genome Project ended and the "genome era" began. Especially because this transition occurred only days before the 50th anniversary of Watson and Crick’s article describing the DNA double helix,² it led to much discussion regarding the future of genetics and genomics and how they would affect biological exploration, health, and even society.^3-8 Now, 2 years into the genome era, is biomedical research any closer to that future, and, if so, what does it look like?

Current and Future Genome Initiatives

Several current genome initiatives afford a look at the future even as they bring it closer. One is an international effort to create a haplotype map (HapMap) to explore variation within the human genome.^9-10 Now rapidly approaching . . . [Full Text of this Article]

Author Affiliations: National Human Genome Research Institute, National Institutes of Health, Bethesda, Md.

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