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Barry J. Marshall, MD

JAMA. 2005;294:1420-1421.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In 1995, the Lasker award I received for clinical medicine helped push Helicobacter pylori across the threshold of global acceptance as the stomach bacterium that causes ulcers and possibly stomach cancer. The most respected scientific award from a US foundation served to drive home the message that the time had come to treat patients with ulcers with antibiotics. Within 2 years of the Lasker award, physicians in developed countries were handed the tools to accomplish the task of curing chronic peptic ulcers. Effective treatments were fast-tracked by the US Food and Drug Administration and new diagnostic tests moved ulcer treatment into the domain of primary care physicians. Ten years later, peptic ulcers are far less common, freeing up billions of health care dollars.

For the medical community and the community at large to accept H pylori as a cause of ulcer disease required a major paradigm . . . [Full Text of this Article]

Author Affiliation: Departments of Medicine and Pharmacology, University of Western Australia, Crawley.

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