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Immunosuppression to Blame

Tracy Hampton, PhD

JAMA. 2005;294:1476-1480.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Chicago—Ever-growing numbers of individuals are at increased risk of developing skin cancer, and not just because of sun worship and the pursuit of the perfect tan. More people are susceptible now because of impaired immunity due to immunosuppressive drugs following organ transplantation or for various rheumatologic and dermatologic conditions. Also vulnerable are patients who have compromised immune surveillance due to such conditions as HIV and chronic lymphocytic leukemia (CLL), which increases their risk of developing cancer.

While such individuals present a challenge to physicians, their conditions can help shed light on the mechanisms involved and may therefore provide opportunities for therapeutic innovations.

TRANSPLANT RECIPIENTS

"Skin cancer is the most common malignancy in the posttransplant setting and affects the majority of patients eventually," said Clark Otley, MD, of the Mayo Clinic and Mayo Medical School, in Rochester, Minn, during the annual meeting of the American Academy of Dermatology held . . . [Full Text of this Article]

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