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	Since this article does not have an abstract, we have provided the first 111 words of the full text and any section headings.

To the Editor: In their study of thrombophilia, Dr Christiansen and colleagues¹ examine the comparative rates of thrombosis in patients with idiopathic and provoked clots, as well as the presence or absence of prothrombotic characteristics in these groups. When considering provoked thrombotic events, particularly in those patients who are in the hospital and are at high risk for clotting, the use of prophylactic measures other than oral anticoagulants (such as subcutaneous heparin or intermittent pneumatic compression devices) will notably influence the outcome of interest. While not mentioned in the protocol, it would be helpful to know if the authors obtained this information and considered this potential bias.

Financial Disclosures: None reported

Bradley Flansbaum, DO, MPH
bflansbaum@lenoxhill.net
Lenox Hill Hospital
New York, NY

1. Christiansen SC, Cannegieter SC, Koster T, Vandenbroucke JP, Rosendaal FR. Thrombophilia, clinical factors, and recurrent venous thrombotic events. JAMA. 2005;293:2352-2361. FREE FULL TEXT

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294:1489.

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