 |
|
Clinical Factors and Recurrent Venous Thrombotic Events—Reply
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
In Reply: We followed up 474 patients with a first deep vein thrombosis for a mean (SD) of 7.3 (2.7) years and found a recurrence rate of 25.9 per 1000 patient-years—33.2 per 1000 patient-years for those with an idiopathic first thrombotic event and 17.7 per 1000 patient-years for those with a provoked first thrombotic event. Of all 90 recurrences, 61 were idiopathic and 29 were provoked (defined as pregnancy, puerperium, use of oral contraceptives within 30 days, or trauma, surgery, immobilization, or use of plaster casts within 3 months before the event).
As Dr Flansbaum suggests, the proportion of provoked events would undoubtedly be higher in the absence of prophylactic measures, such as anticoagulants after surgery. Prophylaxis preventing first thrombotic events would not affect the recurrence rates for provoked and idiopathic events. However, a concern would be whether patients with an idiopathic first thrombotic event were monitored differently than those . . . [Full Text of this Article]
Suzanne C. Cannegieter, MD;
Frits R. Rosendaal, MD
f.r.rosendaal@lumc.nl
Department of Clinical Epidemiology
Leiden University Medical Center
Leiden, the Netherlands
RELATED ARTICLES
Clinical Factors and Recurrent Venous Thrombotic Events
Bradley Flansbaum
JAMA. 2005;294(12):1489.
EXTRACT
| FULL TEXT
Thrombophilia, Clinical Factors, and Recurrent Venous Thrombotic Events
Sverre C. Christiansen, Suzanne C. Cannegieter, Ted Koster, Jan P. Vandenbroucke, and Frits R. Rosendaal
JAMA. 2005;293(19):2352-2361.
ABSTRACT
| FULL TEXT
|
