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  Vol. 294 No. 16, October 26, 2005 TABLE OF CONTENTS
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Increasing Inspired Oxygen to Decrease Surgical Site Infection

Time to Shift the Quality Improvement Research Paradigm

E. Patchen Dellinger, MD

JAMA. 2005;294:2091-2092.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Patients who develop a surgical site infection (SSI) have a 2-fold increase in the length of hospital stay and the risk of death1 and cost the US health care system approximately $1.8 billion per year.2 SSI is the most common preventable adverse outcome after a major operation and is the focus of several major national and international quality improvement initiatives. There is no absolute method to prevent SSI, but more than 30 years of research have shown that proper antibiotic selection and timing, clipping rather than shaving of hair, maintenance of normothermia and normoglycemia, and appropriate surgical technique are critical to reduce the risk.3 For years, surgeons have debated the benefits of higher levels of inspired oxygen in reducing SSI. In this issue of JAMA, Belda and colleagues4 report the results of their clinical trial using different inspired oxygen concentrations intraoperatively and for 6 hours . . . [Full Text of this Article]

Author Affiliation: Department of Surgery, University of Washington School of Medicine, Seattle.



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RELATED ARTICLE

Supplemental Perioperative Oxygen and the Risk of Surgical Wound Infection: A Randomized Controlled Trial
F. Javier Belda, Luciano Aguilera, José García de la Asunción, Javier Alberti, Rosario Vicente, Lucía Ferrándiz, Rafael Rodríguez, Roque Company, Daniel I. Sessler, Gerardo Aguilar, Stephanie García Botello, Rafael Ortí, and for the Spanish Reduccion de la Tasa de Infeccion Quirurgica Group
JAMA. 2005;294(16):2035-2042.
ABSTRACT | FULL TEXT  


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Perioperative Supplemental Oxygen Therapy and Surgical Site Infection: A Meta-analysis of Randomized Controlled Trials
Qadan et al.
Arch Surg 2009;144:359-366.
ABSTRACT | FULL TEXT  

Clinical use of normobaric hyperoxia.
Kuebler
Am. J. Respir. Cell Mol. Bio. 2006;35:404a-4405.
FULL TEXT  

Supplemental Oxygen and Risk of Surgical Wound Infection
Pryor et al.
JAMA 2006;295:1642-1642.
FULL TEXT  

Supplemental perioperative oxygen at 80% FIO2 reduced surgical site infections in elective colorectal surgery
Schmidt
Evid. Based Nurs. 2006;9:52-52.
FULL TEXT  

Supplemental Oxygen for Surgical-Site Infections: The Debate Continues
JWatch Infect. Diseases 2005;2005:5-5.
FULL TEXT  





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