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George F. Sawaya, MD, Discussant

JAMA. 2005;294:2210-2218.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

DR REYNOLDS: Ms G is a 21-year-old woman with a history of abnormal Papanicolaou (Pap) tests.

Ms G first became sexually active at age 19. That year, she had her first gynecologic examination when she visited a doctor to ask for an oral contraceptive pill prescription. Her examination and cytology test were normal. She had annual Pap screening until age 21, when her cytology test (conventional) showed atypical squamous cells of undetermined significance (ASC-US). Her clinician, a nurse practitioner at student health, recommended a repeat cytology test in 6 months. Her repeat test again showed ASC-US, and she was referred to a gynecologist who performed a colposcopy.

On colposcopy, the entire squamocolumnar junction could be seen and her cervix showed grade 1 acetowhite changes. Biopsy revealed metaplasia. A liquid-based cytology test done at the time of the colposcopy was normal. . . . [Full Text of this Article]

MS G: HER VIEW

AT THE CROSSROADS: QUESTIONS FOR DR SAWAYA

Cervical Cancer and ASC-US

Beginning Cervical Cancer Screening

Liquid-Based vs Conventional Cytology

Managing ASC-US: Colposcopy vs Repeat Cytology vs HPV DNA Testing

RECOMMENDATIONS FOR MS G

QUESTIONS AND DISCUSSION

AUTHOR INFORMATION

Author Affiliation: Dr Sawaya is Associate Professor, Department of Obstetrics, Gynecology and Reproductive Sciences; Department of Epidemiology and Biostatistics, University of California, San Francisco; and Director of the Cervical Dysplasia Clinic at San Francisco General Hospital.

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