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A Better Prescription Is Needed

J. Todd Weber, MD

JAMA. 2005;294:2354-2356.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The problem of antimicrobial resistance has been evident almost from the time antimicrobial drugs entered the pharmacopoeia. However, the clinical impact of resistance has been difficult to measure for a variety of reasons, including separating out the effect of underlying illness and the availability of at least 1 effective drug for most infections. Antimicrobial resistance also has economic consequences, but even those have been difficult to quantify.¹ Nevertheless, the decrease in new drug development and increasing resistance to multiple drug classes among various infections require effective interventions now to mitigate the inevitable increase in morbidity and mortality.

Recognizing the potential for serious consequences of resistance to antimicrobial drugs, medical societies, health plans, and insurers, as well as local, state, and federal government agencies, have conducted education and media campaigns to improve use of antimicrobials, with the intent of reducing the evolutionary pressure toward proliferation of resistant . . . [Full Text of this Article]

Author Affiliations: Office of Antimicrobial Resistance, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Ga.

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