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Tracy Hampton, PhD

JAMA. 2005;294:163-164.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

As naturally deadly pathogens that could also be manipulated for use as agents of bioterrorism, the Ebola and Marburg viruses are threats that researchers have sought to overcome for decades.

While there are no approved vaccines or therapies against these pathogens and the often fatal hemorrhagic fevers they cause, a report published July 5 in an online edition of Nature Medicine describes new and promising vaccines that appear to offer complete protection for nonhuman primates infected with the viruses (http://www.nature.com/naturemedicine).

THE FIGHT AGAINST FILOVIRUSES

At press time, the largest and deadliest recorded outbreak of Marburg virus was still ongoing in Angola, with 422 cases reported as of June 17 (356 of which were fatal). Updates of the outbreak can be found at http://www.who.int/csr/don/en/. Ebola virus, a member from the same family (Filoviridae) as Marburg, has also caused significant outbreaks in Africa during the past 3 decades. While Ebola . . . [Full Text of this Article]