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  Vol. 294 No. 22, December 14, 2005 TABLE OF CONTENTS
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Circadian Rhythms and Reperfusion in Patients With Acute ST-Segment Elevation Myocardial Infarction—Reply

Since this article does not have an abstract, we have provided the first 47 words of the full text and any section headings.

In Reply: We agree with Dr Manfredini and colleagues that morning-night variation and circadian rhythms might influence outcomes for patients with myocardial infarction. Future investigations should examine these issues as well as whether the effectiveness of percutaneous coronary intervention shows a circadian variation.

Financial Disclosures: None reported.

David J. Magid, MD, MPH
Clinical Research Unit
Kaiser Permanente
Denver, Colo

Elizabeth H. Bradley, PhD; Harlan M. Krumholz, MD, SM
harlan.krumholz@yale.edu
Yale University School of Medicine
New Haven, Conn

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294:2847.



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Circadian Rhythms and Reperfusion in Patients With Acute ST-Segment Elevation Myocardial Infarction
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Relationship Between Time of Day, Day of Week, Timeliness of Reperfusion, and In-Hospital Mortality for Patients With Acute ST-Segment Elevation Myocardial Infarction
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