
Cognitive Therapy and Preventing Suicide AttemptsReply
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In Reply: Drs Tepper and Whitehead and Messrs Filion and Delaney express concern about several variables that may account for our study results. They suggest that confounding related to either baseline marital and employment status or lack of any treatment during follow-up could be the underlying explanation for the observed difference in repeat suicide attempt rates between the 2 groups.
We created Cox regression models adjusting for these factors. They did not explain the intervention effect when controlling for marital and employment status (hazard ratio [HR], 0.51 [95% confidence interval {CI}, 0.25-1.01]; Wald 21 = 3.72; P = .054). After controlling for lack of treatment during the 18-month follow-up period, we found a HR of 0.41 (95% CI, 0.20-0.80; Wald 21 = 6.42; P = .01). The increased significance of the cognitive therapy effect after controlling for lack of treatment is explained by an association between no treatment and a reduced suicide reattempt rate relative to . . . [Full Text of this Article]
Gregory K. Brown, PhD
gregbrow@mail.med.upenn.edu Department of Psychiatry University of Pennsylvania Philadelphia
Thomas Ten Have, PhD
Center for Clinical Epidemiology and Biostatistics University of Pennsylvania Philadelphia
Gregg R. Henriques, PhD
Department of Graduate Psychology James Madison University Harrisonburg, Va
Sharon X. Xie, PhD
Center for Clinical Epidemiology and Biostatistics University of Pennsylvania Philadelphia
Judd E. Hollander, MD
Department of Emergency Medicine University of Pennsylvania Philadelphia
Aaron T. Beck, MD
Department of Psychiatry University of Pennsylvania Philadelphia
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