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Prophylaxis Against Postoperative Atrial Fibrillation
Current Progress and Future Directions
Mihai V. Podgoreanu, MD;
Joseph P. Mathew, MD
JAMA. 2005;294:3140-3142.
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Atrial fibrillation is by far the most common complication following cardiac surgery, with an incidence consistently reported to range between 27% and 40% and with little change over the past 2 decades.1-5 Postoperative atrial fibrillation is associated with greater resource use as well as neurological, renal, and infectious complications.4 Patients with recurrent episodes of postoperative atrial fibrillation appear to be at the greatest risk for these adverse outcomes.4 Although atrial fibrillation is often less costly than other postsurgical complications, it is clear that the high rate of occurrence and recurrence places substantial financial and clinical burdens on clinicians and patients.2, 6
Many preoperative predictors of postoperative atrial fibrillation have been defined and include advanced age, a history of atrial fibrillation or chronic obstructive pulmonary disease, and valve replacement/repair surgery.2, 4-5 Advanced age has been the most consistent of these predictors with every 10-year increase . . . [Full Text of this Article]
Author Affiliations: Department of Anesthesiology, Duke University Medical Center, Durham, NC.
RELATED ARTICLE
Prophylactic Oral Amiodarone for the Prevention of Arrhythmias That Begin Early After Revascularization, Valve Replacement, or Repair: PAPABEAR: A Randomized Controlled Trial
L. Brent Mitchell, Derek V. Exner, D. George Wyse, Carol J. Connolly, Gregory D. Prystai, Alexander J. Bayes, William T. Kidd, Teresa Kieser, John J. Burgess, André Ferland, Charles L. MacAdams, and Andrew Maitland
JAMA. 2005;294(24):3093-3100.
ABSTRACT
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