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Viral Encephalitis Transmitted From Donor to Organ Recipients
Commentary by Karen L. Roos, MD
JAMA. 2005;294(4):488-489.
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ARCHIVES OF NEUROLOGY
Rabies Encephalomyelitis: Clinical, Neuroradiological, and Pathological Findings in 4 Transplant Recipients
Elizabeth C. Burton, MD; Dennis K. Burns, MD; Michael J. Opatowsky, MD; Waleed H. El-Feky, MD; Bernard Fischbach, MD; Larry Melton, MD, PhD; Edmund Sanchez, MD; Henry Randall, MD; David L. Watkins, MD; Jack Chang, MD; Goran Klintmalm, MD
Background Three patients received solid organ transplants from a common donor and were subsequently discharged from the hospital following an uneventful hospital course. Within 30 days, all 3 organ recipients returned to the hospital with varying symptoms that progressed to rapid neurological deterioration, coma, and death.
Objective To describe the clinical, neuroradiological, and pathological findings of rabies virus infection in organ transplant recipients infected from a common donor.
Design Case series involving a common donor and 3 organ recipients ascertained through review of clinical course and autopsy findings. A fourth case . . . [Full Text of this Article]
Author Affiliations: Department of Neurology, Indiana University School of Medicine, Indianapolis.
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Sarah Ringold, Cassio Lynm, and Richard M. Glass
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EXTRACT
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Rabies Encephalomyelitis: Clinical, Neuroradiological, and Pathological Findings in 4 Transplant Recipients
Elizabeth C. Burton, Dennis K. Burns, Michael J. Opatowsky, Waleed H. El-Feky, Bernard Fischbach, Larry Melton, Edmund Sanchez, Henry Randall, David L. Watkins, Jack Chang, and Goran Klintmalm
Arch Neurol. 2005;62(6):873-882.
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